Author's response to reviews Title:Understanding of Chest Pain in Microvascular Disease Proved by Cardiac Magnetic Resonance Image (UMPIRE): Study Protocol for a Randomized Controlled Trial Authors:

Understanding of chest pain in microvascular disease proved by cardiac magnetic resonance image (UMPIRE): study protocol for a randomized controlled trial

BACKGROUND Microvascular angina (MVA) is characterized by anginal chest pain, an abnormal stress test, and normal coronary arteries on coronary angiography. Although the exact pathogenesis remains unclear, endothelial dysfunction is a contributing factor. To date, there exists no specific therapy for this disease. Phosphodiesterase-5 inhibitor improves the endothelial function and subsequently ...

How Effective Is the Use of Metaphor Therapy on Reducing Psychological Symptoms and Pain Discomfort in Patients with Non-Cardiac Chest Pain: A Randomized, Controlled Trial

Introduction: Psychological symptoms of non-cardiac chest pain (NCCP) including perceptual, emotional, and behavioral problems can effect patient perception of chest pain. This study was conducted to determine the effect of metaphor therapy on mitigating depression, anxiety, stress, and pain discomfort in patients with NCCP. Materials and Methods: This randomized, controlled, trial was conducte...

Author's response to reviews Title:Electroacupuncture for postoperative pain and gastrointestinal motility after laparoscopic appendectomy (AcuLap trial): study protocol for a prospective randomized controlled trial with three-arm, parallel-group (electroacupuncture versus sham acupuncture versus control) Authors:

Title:Electroacupuncture for postoperative pain and gastrointestinal motility after laparoscopic appendectomy (AcuLap trial): study protocol for a prospective randomized controlled trial with three-arm, parallel-group (electroacupuncture versus sham acupuncture versus control)

Author’s response to reviews Title: Magnetic Resonance Adenosine Perfusion Imaging as Gatekeeper of Invasive Coronary Intervention (MAGnet): study protocol for a randomized controlled trial Authors:

Title: Magnetic Resonance Adenosine Perfusion Imaging as Gatekeeper of Invasive Coronary Intervention (MAGnet): study protocol for a randomized controlled trial Authors: Dominik Buckert ([email protected]) Simon Witzel ([email protected]) Maciej Cieslik ([email protected]) Raid Tibi ([email protected]) Wolfgang Rottbauer ([email protected]...

Author's response to reviews Title: Intermittent preventive treatment: efficacy and safety of sulfadoxine-pyrimethamine and sulfadoxine-pyrimethamine plus piperaquine regimens in schoolchildren of the Democratic Republic of Congo. A study protocol for a randomized controlled trial Authors: